Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 12/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | HPGD | P15428 | 6/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.63 |
| ▸ | TP53 | P04637 | 8/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.63 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.63 |
| ▸ | AR | P10275 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2746872 | 0.83 | MEN1 (0.90) | MEN1KMT2ACYP3A4HSD17B10MAPK1 | |
| SCHEMBL12892177 | 0.80 | ACP1 (0.53) | MEN1KMT2ACYP3A4HSD17B10MAPK1 | |
| SCHEMBL10453856 | 0.79 | HCRTR1 (0.51) | MEN1KMT2ACYP3A4HSD17B10MAPK1 | |
| SCHEMBL10453899 | 0.79 | CASP3 (0.51) | MEN1KMT2ACYP3A4HSD17B10MAPK1 | |
| SCHEMBL345696 | 0.79 | MEN1 (1.00) | MEN1KMT2ACYP3A4HSD17B10MAPK1 | |
| SCHEMBL76636 | 0.79 | KDM4E (0.93) | MEN1KMT2ACYP3A4HSD17B10MAPK1 | |
| Flavonol SCHEMBL1679068 | 0.79 | KDM4E (1.00) | MEN1KMT2ACYP3A4HSD17B10MAPK1 | |
| Flavonol SCHEMBL20246 | 0.79 | KDM4E (1.00) | MEN1KMT2ACYP3A4HSD17B10MAPK1 | |
| Flavonol SCHEMBL29433939 | 0.79 | KDM4E (1.00) | MEN1KMT2ACYP3A4HSD17B10MAPK1 | |
| SCHEMBL8711671 | 0.77 | DDR2 (0.56) | MEN1KMT2ACYP3A4HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |