Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 9/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 8/20 | 0.40 |
| ▸ | CDK1 | P06493 | 3/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | MAP2 | P11137 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24046989 | 0.85 | TNKS (0.51) | TNKSCYP1B1CYP1A2CYP1A1AR | |
| SCHEMBL24046996 | 0.83 | CYP1B1 (0.49) | TNKSCYP1B1CYP1A2CYP1A1CDK1 | |
| SCHEMBL31632272 | 0.72 | TNKS (0.53) | TNKSCYP1B1CYP1A2CYP1A1AR | |
| SCHEMBL24046903 | 0.70 | GABRP (0.52) | TNKSCYP1B1CYP1A2CYP1A1CSNK2A2 | |
| SCHEMBL4324696 | 0.69 | CYP3A4 (0.50) | CYP11B1CYP11B2 | |
| SCHEMBL24046894 | 0.69 | TNKS (0.56) | TNKSCYP1B1CYP1A2ARCSNK2A2 | |
| SCHEMBL24046901 | 0.67 | CSNK2A2 (0.45) | TNKSCYP1B1CYP1A2CYP1A1AR | |
| SCHEMBL4649989 | 0.67 | CSNK2A2 (0.62) | TNKSCYP1B1CYP1A2CYP1A1CDK1 | |
| SCHEMBL21801263 | 0.67 | CSNK2A2 (0.52) | TNKSCYP1B1CYP1A2CYP1A1AR | |
| SCHEMBL31632287 | 0.67 | TNKS (0.53) | TNKSCYP1B1CYP1A2CYP1A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |