Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10205828 | 0.92 | ALDH1A1 (0.60) | TDP1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL31393236 | 0.84 | TDP1 (0.55) | TDP1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL31393252 | 0.84 | TDP1 (0.55) | TDP1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL12339168 | 0.78 | KMT2A (0.73) | TDP1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL26867246 | 0.78 | TDP1 (0.79) | TDP1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL16659834 | 0.78 | TDP1 (0.79) | TDP1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL2911515 | 0.76 | TDP1 (0.59) | TDP1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL2907266 | 0.76 | TDP1 (0.59) | TDP1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10697834 | 0.76 | L3MBTL1 (0.57) | TDP1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29105358 | 0.76 | NPC1 (0.57) | TDP1MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210363159-A1 | HETEROCYCLIC COMPOUND FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210363159-A1 | HETEROCYCLIC COMPOUND FOR USE IN ELECTRONIC DEVICES | DDT, NQO1, CYP2E1 | TDP1 1797/4885MEN1 1174/4885KMT2A 722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.