Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 16/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 6/20 | 1.00 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.67 |
| ▸ | HTR2A | P28223 | 1/20 | 0.64 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2410329 | 0.96 | MPO (1.00) | MPOSLC6A4NOTUMHTR2ATRPM8 | |
| SCHEMBL5203631 | 0.89 | MPO (0.80) | MPOSLC6A4NOTUMHTR2ATRPM8 | |
| SCHEMBL28682971 | 0.89 | MPO (0.80) | MPOSLC6A4NOTUMHTR2AHTR1A | |
| SCHEMBL5792523 | 0.87 | MPO (0.78) | MPOSLC6A4NOTUMTSHRMTNR1A | |
| SCHEMBL5344966 | 0.84 | MPO (0.80) | MPOSLC6A4NOTUMHTR2ATRPM8 | |
| SCHEMBL5792142 | 0.84 | MPO (0.73) | MPOSLC6A4NOTUMMTNR1AMTNR1B | |
| SCHEMBL2177075 | 0.84 | TSHR (0.75) | MPOSLC6A4NOTUMHTR2ATRPM8 | |
| SCHEMBL5338627 | 0.83 | MPO (0.78) | MPOSLC6A4NOTUMHTR2ATRPM8 | |
| SCHEMBL28673230 | 0.83 | MPO (0.71) | MPOSLC6A4NOTUMHTR2AHTR1A | |
| SCHEMBL28680989 | 0.83 | MPO (0.71) | MPOSLC6A4HTR2AHTR1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4592401-A2 | CHEMICAL COMPOSITIONS AND METHODS OF USING THE SAME | Bruker Spatial Biology, Inc. (US) | 2025-07-30 | — | — | EP | disclosed |
| EP-4214331-B1 | CHEMICAL COMPOSITIONS AND METHODS OF USING THE SAME | BRUKER SPATIAL BIOLOGY INC (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-117120629-A | Chemical compositions and methods of use thereof | 纳米线科技公司 | 2023-11-24 | — | — | CN | disclosed |
| US-20230366012-A1 | CHEMICAL COMPOSITIONS AND METHODS OF USING THE SAME | BRUKER SPATIAL BIOLOGY, INC. | 2023-11-16 | — | — | US | disclosed |
| CN-113943244-A | Sulfur-containing gamma, gamma-diindolyl butyramide compound prepared by double-functionalization reaction | 温州大学 | 2022-01-18 | — | — | CN | disclosed |
| US-20120122948-A1 | 3-ALKYL-5-FLUOROINDOLE DERIVATIVES AS MYELOPEROXIDASE INHIBITORS | UNIVERSITE LIBRE DE BEUXELLES (BE) | 2012-05-17 | — | — | US | disclosed |
| EP-0745584-B1 | Arylalkyl(thio) carboxamides compounds with affinity for melatonine receptors, processes for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-01-05 | — | — | EP | disclosed |
| US-5721276-A | TREATING DISORDERS OF MELATONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1998-02-24 | — | — | US | disclosed |
| EP-0745584-A1 | Arylalkyl(thio) carboxamides compounds with affinity for melatonine receptors, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-12-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122948-A1 | 3-ALKYL-5-FLUOROINDOLE DERIVATIVES AS MYELOPEROXIDASE INHIBITORS | MPO, SERPINB1, MAOA | MPO 1/4885SLC6A4 460/4885NOTUM 386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.