Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 17/20 | 0.69 |
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24052314 | 0.86 | TLR8 (0.73) | TLR8TLR7ADORA3MAPTNPSR1 | |
| SCHEMBL25627708 | 0.82 | TLR8 (0.69) | TLR8TLR7ADORA3MAPTNPSR1 | |
| SCHEMBL26100478 | 0.81 | TLR8 (0.83) | TLR8TLR7ADORA3MAPTNPSR1 | |
| SCHEMBL24052764 | 0.79 | TLR8 (0.72) | TLR8TLR7MAPTNPSR1 | |
| SCHEMBL482958 | 0.78 | TLR8 (1.00) | TLR8TLR7 | |
| SCHEMBL29373816 | 0.78 | TLR8 (1.00) | TLR8TLR7 | |
| SCHEMBL4540442 | 0.78 | TLR8 (0.74) | TLR8TLR7ADORA3 | |
| Hydrochloric Acid SCHEMBL5765916 | 0.76 | TLR8 (0.97) | TLR8TLR7 | |
| SCHEMBL4540446 | 0.76 | TLR8 (0.88) | TLR8TLR7ADORA3 | |
| SCHEMBL24052769 | 0.76 | TLR8 (0.88) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230181743-A1 | FUNCTIONAL LIPID DERIVATIVES AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230181743-A1 | FUNCTIONAL LIPID DERIVATIVES AND USES THEREOF | LIPA, LIPG, LIPC | TLR8 531/4885TLR7 1104/4885ADORA3 1170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.