⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27576989 | 0.98 | HDAC8 (0.36) | — | |
| Fluoride SCHEMBL27814813 | 0.98 | HDAC8 (0.36) | — | |
| Hydrochloric Acid SCHEMBL27764638 | 0.74 | HDAC8 (0.36) | — | |
| SCHEMBL27785439 | 0.70 | KAT7 (0.37) | — | |
| Sulfuric Acid SCHEMBL27769600 | 0.64 | SLC6A3 (0.37) | — | |
| SCHEMBL27614756 | 0.62 | — | — | |
| SCHEMBL1348269 | 0.60 | KDM4E (0.32) | — | |
| SCHEMBL1416134 | 0.60 | L3MBTL1 (0.46) | — | |
| SCHEMBL3474793 | 0.59 | ADORA3 (0.55) | — | |
| SCHEMBL195296 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107635676-B | Pretreatment method for electroless plating | 麦克德米德股份有限公司 | 2020-09-18 | — | — | CN | claimed |
| EP-2630129-B1 | QUINOXALINE DERIVATES | MERCK PATENT GMBH (DE) | 2016-10-26 | — | — | EP | claimed |
| US-8895559-B2 | Quinoxalines derivatives and pharmaceutical compositions and kits | MERCK PATENT GMBH (DE) | 2014-11-25 | — | — | US | claimed |
| US-20130217670-A1 | QUINOXALINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2013-08-22 | — | — | US | claimed |
| EP-2297166-B1 | SUBSTITUTED N-IMIDAZO[2,1-B]THIAZOLE-5-SULFONAMIDE DERIVATIVES AS 5-HT6 LIGANDS | ESTEVE LABOR DR (ES) | 2012-08-01 | — | — | EP | claimed |
| CN-101454289-B | Substituted tetrahydroisoquinoline compounds, their preparation and use in medicine | ESTEVE LABOR DR | 2012-07-04 | — | — | CN | claimed |
| CN-101627033-A | The heterocyclyl-substituted sulfonamides that is used for the treatment of cognition or food ingestion related disorders | ESTEVE LABOR DR | 2010-01-13 | — | — | CN | claimed |
| WO-2009135925-A1 | SUBSTITUTED N-IMIDAZO[2,1-B]THIAZOLE-5-SULFONAMIDE DERIVATIVES AS 5-HT6 LIGANDS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2009-11-12 | — | — | WO | claimed |
| WO-2009135927-A1 | SUBSTITUTED N-PHENYL-2,3-DIHYDROIMIDAZO[2,1-B]THIAZOLE-5-SULFONAMIDE DERIVATIVES AS 5-HT6 LIGANDS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2009-11-12 | — | — | WO | claimed |
| EP-2116546-A1 | Substituted N-phenyl-2,3-dihydroimidazo[2,1-b]thiazole-5-sulfonamide derivatives as 5-HT6 ligands | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2009-11-11 | — | — | EP | claimed |
| EP-2116547-A1 | Substituted N-imidazo(2, 1-b) thiazole-5-sulfonamide derivatives as 5-TH6 ligands | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2009-11-11 | — | — | EP | claimed |
| CN-101454289-A | Substituted tetrahydroisoquinoline compounds, their preparation and use in medicine | ESTEVE LABOR DR (ES) | 2009-06-10 | — | — | CN | claimed |
| CN-101410116-A | Urotensin II receptor antagonists | JANSSEN PHARMACEUTICA NV (BE) | 2009-04-15 | — | — | CN | claimed |
| CN-101272785-A | Tetrahydro- beta-carbolin-sulfonamide derivatives as 5-HT6 ligands | ESTEVE LABOR DR (ES) | 2008-09-24 | — | — | CN | claimed |
| CN-1665802-A | Bisarylsulfonamide compounds and their use in cancer therapy | CYCLACEL LTD (GB) | 2005-09-07 | — | — | CN | claimed |
| CN-1048856-A | Cephalosporins derivatives and preparation method thereof | HOECHST AG (DE) | 1991-01-30 | — | — | CN | claimed |
| CN-107635676-B | Pretreatment method for electroless plating | 麦克德米德股份有限公司 | 2020-09-18 | — | — | CN | disclosed |
| CN-103224488-A | Heterocyclic compound or salt thereof | OTSUKA PHARMA CO LTD | 2013-07-31 | — | — | CN | disclosed |
| US-4011210-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1977-03-08 | — | — | US | disclosed |
| US-3939172-A | OR 4-TRIFLUOROACETAMIDO-THIAZOLE OR SALTS, INTERMEDIATES | SMITHKLINE CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |