Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC2 | O75106 | 13/20 | 0.42 |
| ▸ | MAOA | P21397 | 5/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23779151 | 1.00 | AOC2 (0.42) | AOC2MAOAAOC3MAOB | |
| SCHEMBL23779153 | 1.00 | AOC2 (0.42) | AOC2MAOAAOC3MAOB | |
| SCHEMBL24025474 | 1.00 | AOC2 (0.42) | AOC2MAOAAOC3MAOB | |
| SCHEMBL24025531 | 1.00 | AOC2 (0.42) | AOC2MAOAAOC3MAOB | |
| SCHEMBL24058230 | 0.90 | AOC2 (0.42) | AOC2MAOAAOC3MAOB | |
| SCHEMBL30916739 | 0.89 | AOC2 (0.44) | AOC2MAOAAOC3MAOB | |
| SCHEMBL24058229 | 0.88 | AOC2 (0.42) | AOC2MAOAAOC3MAOB | |
| SCHEMBL24025653 | 0.86 | AOC2 (0.47) | AOC2MAOAAOC3MAOB | |
| SCHEMBL24025478 | 0.86 | AOC2 (0.47) | AOC2MAOAAOC3MAOB | |
| SCHEMBL24058323 | 0.86 | AOC2 (0.47) | AOC2MAOAAOC3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3873600-B9 | PYRIDINYL SULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2024-02-14 | — | — | EP | disclosed |
| EP-3873600-B1 | PYRIDINYL SULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2023-09-20 | — | — | EP | disclosed |
| US-20210361637-A1 | PYRIDINYL SULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210361637-A1 | PYRIDINYL SULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | ARSA, SULT1A1, SULT2A1 | AOC2 4191/4885MAOA 361/4885AOC3 4034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.