SCHEMBL24059145

SCHEMBL24059145

Cc1cn(C2CC(O[Si](C)(C)C(C)(C)C)[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.64

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.62
TK1 P04183 5/20 0.59
LMNA P02545 2/20 0.57
TSHR P16473 2/20 0.57
ALB P02768 1/20 0.57
PKM P14618 1/20 0.57
BLM P54132 1/20 0.57
PMP22 Q01453 1/20 0.57
CYP2D6 P10635 1/20 0.57
TK2 O00142 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15354282 1.00 RNASE1 (0.62) RNASE1TK1LMNATSHRALB
SCHEMBL2056757 1.00 RNASE1 (0.62) RNASE1TK1LMNATSHRALB
SCHEMBL25747162 1.00 RNASE1 (0.62) RNASE1TK1LMNATSHRALB
SCHEMBL25797545 1.00 RNASE1 (0.62) RNASE1TK1LMNATSHRALB
SCHEMBL24059196 1.00 RNASE1 (0.62) RNASE1TK1LMNATSHRALB
SCHEMBL733403 1.00 RNASE1 (0.62) RNASE1TK1LMNATSHRALB
SCHEMBL8424862 0.92 RNASE1 (0.53) RNASE1TK1LMNAALBPKM
SCHEMBL8424863 0.92 RNASE1 (0.53) RNASE1TK1LMNAALBPKM
SCHEMBL10079072 0.91 TOP2A (0.54) RNASE1TK1
SCHEMBL14788961 0.91 TOP2A (0.54) RNASE1TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212204-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS THE SCRIPPS RESEARCH INSTITUTE 2023-07-06 US disclosed
WO-2021234459-A9 DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD. (SG) 2022-02-03 WO disclosed
WO-2021234459-A2 DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD. (SG) 2021-11-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212204-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS PNKP, POLL, RNGTT RNASE1 540/4885TK1 345/4885LMNA 3270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.