Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.53 |
| ▸ | TOP2A | P11388 | 4/20 | 0.53 |
| ▸ | TK1 | P04183 | 6/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8424863 | 1.00 | RNASE1 (0.53) | RNASE1TOP2ATK1ALBPKM | |
| SCHEMBL8905738 | 0.94 | RNASE1 (0.52) | RNASE1TOP2ATK1ALBPKM | |
| SCHEMBL733403 | 0.92 | RNASE1 (0.62) | RNASE1TK1ALBPKMLMNA | |
| SCHEMBL2056757 | 0.92 | RNASE1 (0.62) | RNASE1TK1ALBPKMLMNA | |
| SCHEMBL25747162 | 0.92 | RNASE1 (0.62) | RNASE1TK1ALBPKMLMNA | |
| SCHEMBL24059145 | 0.92 | RNASE1 (0.62) | RNASE1TK1ALBPKMLMNA | |
| SCHEMBL24059196 | 0.92 | RNASE1 (0.62) | RNASE1TK1ALBPKMLMNA | |
| SCHEMBL15354282 | 0.92 | RNASE1 (0.62) | RNASE1TK1ALBPKMLMNA | |
| SCHEMBL25797545 | 0.92 | RNASE1 (0.62) | RNASE1TK1ALBPKMLMNA | |
| SCHEMBL8428654 | 0.90 | TK1 (0.53) | RNASE1TOP2ATK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5892024-A | Bifunctional nucleosides, oligomers thereof, and methods of making and using the same | SANOFI (FR) | 1999-04-06 | — | — | US | disclosed |
| US-5677439-A | PREVENTION GENE EXPRESSION | SANOFI (FR) | 1997-10-14 | — | — | US | disclosed |
| EP-0541722-B1 | COMPOUNDS AND METHODS FOR INHIBITING GENE EXPRESSION | STERLING WINTHROP INC (US) | 1995-12-20 | — | — | EP | disclosed |