SCHEMBL24060739

SCHEMBL24060739

CC(C)CCc1ccc(=O)[nH]c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ALDH1A1 P00352 1/20 0.38
DAO P14920 2/20 0.37
LMNA P02545 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34
DHODH Q02127 1/20 0.34
TRPV6 Q9H1D0 1/20 0.34
GPR84 Q9NQS5 1/20 0.33
RORC P51449 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
SORT1 Q99523 1/20 0.33
OPRM1 P35372 1/20 0.33
OPRK1 P41145 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRA3 P34903 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14466655 0.86 GAA (0.38) GAASMN1; SMN2DAOLMNAMEN1
SCHEMBL13772689 0.80 GAA (0.54) GAASMN1; SMN2ALDH1A1LMNAMEN1
SCHEMBL12844536 0.78 GPR84 (0.42) ALDH1A1LMNAMEN1KMT2AMAPT
SCHEMBL9495098 0.74 ALDH1A1 (0.41) GAASMN1; SMN2ALDH1A1DAOLMNA
SCHEMBL28815221 0.74 ALDH1A1 (0.41) GAASMN1; SMN2ALDH1A1DAOLMNA
SCHEMBL3057964 0.74 TAAR1 (0.41) SMN1; SMN2ALDH1A1MEN1KMT2AMAPT
SCHEMBL8080450 0.73 HTT (0.41) SMN1; SMN2DHODHOPRK1
SCHEMBL21459417 0.73 HRH3 (0.50) ALDH1A1
SCHEMBL7466221 0.73 MAPT (0.51) ALDH1A1LMNAMAPTGPR84HIF1A
SCHEMBL18595187 0.73 GAA (0.39) GAASMN1; SMN2ALDH1A1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3658570-B1 TYROSINASE ANTISENSE OLIGONUCLEOTIDES OLIPASS CORP (KR) 2021-12-01 EP disclosed