Dimethylamine

Dimethylamine

SCHEMBL2406110

CCc1ccccc1C(=O)O.CNC

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CLCN2 P51788 2/20 0.59
FOLH1 Q04609 1/20 0.55
TSHR P16473 1/20 0.55
ALDH1A1 P00352 3/20 0.52
ALOX15 P16050 1/20 0.52
HIF1A Q16665 2/20 0.49
CYP2C9 P11712 1/20 0.49
HTT P42858 2/20 0.49
KMT2A Q03164 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
SLC16A3 O15427 1/20 0.47
AKR1C3 P42330 1/20 0.47
CA12 O43570 2/20 0.45
CA9 Q16790 2/20 0.45
KDM4E B2RXH2 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
HMGB1 P09429 1/20 0.45
HPGD P15428 1/20 0.45
CA4 P22748 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28115 0.94 FOLH1 (0.61) CLCN2FOLH1TSHRALDH1A1ALOX15
SCHEMBL6916475 0.91 FOLH1 (0.59) CLCN2FOLH1TSHRALDH1A1ALOX15
Ammonia Solution, Strong SCHEMBL22042013 0.91 FOLH1 (0.59) CLCN2FOLH1TSHRALDH1A1ALOX15
SCHEMBL6915613 0.91 FOLH1 (0.59) CLCN2FOLH1TSHRALDH1A1ALOX15
SCHEMBL6912943 0.91 FOLH1 (0.59) CLCN2FOLH1TSHRALDH1A1ALOX15
Bromide SCHEMBL3173857 0.91 FOLH1 (0.59) CLCN2FOLH1TSHRALDH1A1ALOX15
SCHEMBL6914507 0.91 FOLH1 (0.59) CLCN2FOLH1TSHRALDH1A1ALOX15
SCHEMBL6914874 0.91 FOLH1 (0.59) CLCN2FOLH1TSHRALDH1A1ALOX15
SCHEMBL6912613 0.91 FOLH1 (0.59) CLCN2FOLH1TSHRALDH1A1ALOX15
SCHEMBL6914562 0.91 FOLH1 (0.59) CLCN2FOLH1TSHRALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2550250-B1 AMINE SYNERGISTS AND THEIR USE IN RADIATION CURING SUN CHEMICAL BV (NL) 2020-06-24 EP disclosed
US-10059807-B2 Gels AORTECH INTERNATIONAL PLC (GB) 2018-08-28 US disclosed
US-20170121464-A1 GELS AORTECH BIOMATERIALS PTY LTD. (AU) 2017-05-04 US disclosed
EP-2853253-A2 Dental curable composition containing particles with different refractive indexes Shofu Inc. (JP) 2015-04-01 EP disclosed
US-8952190-B2 Synergists SUN CHEMICAL B.V. (NL) 2015-02-10 US disclosed
US-8445581-B2 Biocompatible polymer compositions POLYNOVO BIOMATERIALS PTY LIMITED (AU) 2013-05-21 US disclosed
EP-2550250-A2 AMINE SYNERGISTS AND THEIR USE IN RADIATION CURING Sun Chemical B.V. (NL) 2013-01-30 EP disclosed
US-20130012611-A1 SYNERGISTS SUN CHEMICAL B.V. (NL) 2013-01-10 US disclosed
WO-2011117591-A2 SYNERGISTS SUN CHEMICAL B.V. (NL) 2011-09-29 WO disclosed
US-20090324675-A1 BIOOCOMPATIBLE POLYMER COMPOSITIONS POLYNOVO BIOMATERIALS PTY LIMITED (AU) 2009-12-31 US disclosed
EP-1462079-B1 Dental composition G C DENTAL IND CORP (JP) 2007-05-23 EP disclosed
US-7041164-B2 Dental etch solutions Kanca, III, John A. (US) 2006-05-09 US disclosed
CN-1667071-A Adhesive composition, adhesive sheets and surface protective film NITTO DENKO CORP (JP) 2005-09-14 CN disclosed
EP-0923924-B1 Dental adhesive kit SUN MEDICAL CO LTD (JP) 2005-03-09 EP disclosed
EP-1462079-A1 Dental composition GC Corporation (JP) 2004-09-29 EP disclosed
US-6794481-B2 THERMOSETTING RESIN OR A PHOTOCURABLE RESIN AND ITS INTERMEDIATE PRODUCT EACH OF WHICH IS SUITABLE FOR USE IN ELECTRONICS FIELDS REQUIRING LOW DIELECTRIC CONSTANT, LOW DIELECTRIC LOSS TANGENT AND HIGH TOUGHNESS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-09-21 US disclosed
US-20030175218-A1 Device for dental applications INTER-MED, INC. 2003-09-18 US disclosed
US-20030130438-A1 Bifunctional phenylene ether oligomer, its derivatives its use and process for the production thereof MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2003-07-10 US disclosed
US-6288138-B1 Dental adhesive kit SUN MEDICAL CO., LTD. (JP) 2001-09-11 US disclosed
EP-0923924-A2 Dental adhesive kit SUN MEDICAL CO., LTD. (JP) 1999-06-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130012611-A1 SYNERGISTS RAD51, MRE11, RAD52 CLCN2 4821/4885FOLH1 3120/4885TSHR 2245/4885
US-20090324675-A1 BIOOCOMPATIBLE POLYMER COMPOSITIONS HPGDS, PGF, PIGS CLCN2 4113/4885FOLH1 4067/4885TSHR 4884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.