Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PDE9A | O76083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21095848 | 0.90 | KIF11 (0.36) | ARALDH1A1GLAGAAHPGD | |
| SCHEMBL12829127 | 0.83 | KIF11 (0.35) | KIF11SMN1; SMN2 | |
| SCHEMBL18265626 | 0.83 | KIF11 (0.35) | KIF11SMN1; SMN2 | |
| SCHEMBL16604334 | 0.83 | KIF11 (0.47) | ARALDH1A1GAAKIF11LMNA | |
| SCHEMBL13199009 | 0.82 | AR (0.38) | ARTRPV4ALDH1A1GLAGAA | |
| SCHEMBL15605539 | 0.82 | CYP11B2 (0.40) | ALDH1A1GLAGAAHPGDKIF11 | |
| SCHEMBL18887633 | 0.82 | TRPV4 (0.34) | ARTRPV4ALDH1A1GLAGAA | |
| SCHEMBL14768754 | 0.81 | KIF11 (0.36) | ARALDH1A1GLAGAAHPGD | |
| SCHEMBL18887791 | 0.81 | HPGD (0.37) | ARALDH1A1GLAGAAHPGD | |
| SCHEMBL21498301 | 0.81 | TRPV4 (0.38) | ARTRPV4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3117288-B1 | ELECTRO-RHEOLOGICAL FLUID AND HAPTIC DEVICE | MERCK PATENT GMBH (DE) | 2021-12-01 | — | — | EP | disclosed |