Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | TACR2 | P21452 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 2/20 | 0.36 |
| ▸ | MC5R | P33032 | 2/20 | 0.36 |
| ▸ | MC3R | P41968 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 3/20 | 0.34 |
| ▸ | CCND1 | P24385 | 3/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.34 |
| ▸ | HTR1F | P30939 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2403466 | 0.89 | HTR2A (0.41) | HTR2AHTR2CHTR2BTACR2FFAR1 | |
| SCHEMBL1968625 | 0.87 | TACR2 (0.53) | HTR2AHTR2CHTR2BTACR2MC4R | |
| SCHEMBL2410775 | 0.86 | MPO (0.41) | TACR2GPR84MC4RMC5RMC3R | |
| SCHEMBL2406656 | 0.84 | GPR84 (0.44) | HTR2ATACR2GPR84MC4RMC5R | |
| SCHEMBL2405988 | 0.84 | HTR1A (0.43) | HTR2ATACR2 | |
| SCHEMBL1969998 | 0.83 | CDK4 (0.51) | TACR2GPR84MC4RMC5RMC3R | |
| SCHEMBL2405096 | 0.80 | TACR2 (0.43) | HTR2AHTR2CHTR2BTACR2MC4R | |
| SCHEMBL2405302 | 0.80 | TACR2 (0.43) | HTR2AHTR2CHTR2BTACR2MC4R | |
| SCHEMBL2404161 | 0.80 | TACR2 (0.43) | TACR2GPR84MC4RMC5RMC3R | |
| SCHEMBL1972300 | 0.80 | CDK4 (0.49) | TACR2MC4RMC5RMC3RCDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-01 | — | — | US | claimed |
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | HCRTR2, HCRTR1, HRH3 | HTR2A 46/4885HTR2C 80/4885HTR2B 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.