SCHEMBL2406290

SCHEMBL2406290

CCCCCC=C[PH](=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.50
PPARD Q03181 4/20 0.50
PPARA Q07869 4/20 0.50
TERT O14746 3/20 0.50
PTPN1 P18031 3/20 0.50
MAPT P10636 3/20 0.50
BLM P54132 3/20 0.50
HSD17B10 Q99714 3/20 0.50
FABP4 P15090 3/20 0.50
KMT2A Q03164 3/20 0.50
TOP1 P11387 3/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2C19 P33261 2/20 0.50
FAAH O00519 2/20 0.50
USP2 O75604 2/20 0.50
LMNA P02545 2/20 0.50
ALOX15 P16050 2/20 0.50
RECQL P46063 2/20 0.50
CYP19A1 P11511 2/20 0.50
NR4A2 P43354 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5706293 0.98 TERT (0.53) PPARGPPARDPPARATERTPTPN1
SCHEMBL10439719 0.98 TERT (0.53) PPARGPPARDPPARATERTPTPN1
SCHEMBL5706294 0.98 TERT (0.53) PPARGPPARDPPARATERTPTPN1
SCHEMBL28360411 0.98 TERT (0.53) PPARGPPARDPPARATERTPTPN1
SCHEMBL2405654 0.93
SCHEMBL10490215 0.85 F7 (0.41) PPARGPPARDPPARATERTPTPN1
Phosphonic Acid SCHEMBL1204428 0.81 FAAH (0.62) PPARGPPARDPPARATERTPTPN1
Phosphonic Acid SCHEMBL8415181 0.81 FAAH (0.62) PPARGPPARDPPARATERTPTPN1
Phosphonic Acid SCHEMBL3140402 0.81 FAAH (0.62) PPARGPPARDPPARATERTPTPN1
SCHEMBL10439717 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8772519-B2 Process for preparing mono-allyl-functionalized dialkylphosphinic acids, salts and esters thereof with allylic compounds, and the use thereof CLARIANT FINANCE (BVI) LIMITED (VG) 2014-07-08 US disclosed
US-20110213080-A1 Process for Preparing Mono-Allyl-Functionalized Dialkylphosphinic Acids, Salts and Esters Thereof With Allylic Compounds, and the Use Thereof CLARIANT FINANCE (BVI) LIMITED (VG) 2011-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110213080-A1 Process for Preparing Mono-Allyl-Functionalized Dialkylphosphinic Acids, Salts and Esters Thereof With Allylic Compounds, and the Use Thereof AGL, ACSL3, ACSL6 PPARG 1595/4885PPARD 4156/4885PPARA 1397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.