Flucytosine

Flucytosine

SCHEMBL24063

Nc1nc(=O)[nH]cc1F

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

TMP1

The experimentally established mechanism targets of Flucytosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flucytosine SCHEMBL8160959 1.00 ALDH1A1 (0.37)
Flucytosine SCHEMBL3868918 0.98 ALDH1A1 (0.35)
Flucytosine SCHEMBL28748160 0.98
Flucytosine SCHEMBL29100530 0.98 ALDH1A1 (0.35)
Flucytosine SCHEMBL3871370 0.98 ALDH1A1 (0.35)
Flucytosine SCHEMBL3869716 0.98 ALDH1A1 (0.35)
Flucytosine SCHEMBL3870974 0.98 ALDH1A1 (0.35)
Flucytosine SCHEMBL1050449 0.96 ALDH1A1 (0.34)
Flucytosine SCHEMBL3867430 0.94 ALDH1A1 (0.33)
Flucytosine SCHEMBL27696081 0.94 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 46575 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US claimed
WO-2026107113-A1 MODIFIED CELLS FOR PROGRAMMING EXTRA ENVELOPED VIRUSES (EEVs) AND THEIR USE FOR PRODUCING THE EEVs, THE PROGRAMMED EEVs AND USES THEREOF CALIDI BIOTHERAPEUTICS (NEVADA), INC. (US) 2026-05-21 WO claimed
US-20260124224-A1 USE OF COMBINED COMPOSITION IN PREPARING DRUG FOR RESISTING FUNGAL AND BACTERIAL INFECTIONS NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY (CN) 2026-05-07 US claimed
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 EP claimed
US-12618050-B2 Engineered polypeptides that exhibit increased catalytic efficiency for unnatural cofactors and uses thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-05 US claimed
EP-4726042-A2 ANTISENSE OLIGOMERS TARGETING SETD5 FOR UPREGULATION AND USE THEREOF Korea Advanced Institute of Science and Technology (KR) 2026-04-15 EP claimed
EP-4719384-A2 COMPOUNDS WITH ANTIFUNGAL PROPERTIES Trustees of Dartmouth College (US) 2026-04-08 EP claimed
US-12582696-B2 Debaryomyces species as an indicator of non-healing ulcers in Crohn's disease WASHINGTON UNIVERSITY (US) 2026-03-24 US claimed
EP-4710766-A1 MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE BASF SE (DE) 2026-03-18 EP claimed
EP-4704904-A1 TETRAZINE-BASED TARGETING AGENTS FOR IN VIVO DELIVERY OF A PAYLOAD Tambo, Inc. (US) 2026-03-11 EP claimed
US-4703121-A Process for the preparation of 5-fluorocytosine BAYER AKTIENGESELLSCHAFT (DE) 1987-10-27 US claimed
EP-0214265-A1 ANTIGENS, ANTIBODIES AND THEIR USES CORAL SOCIEDADE BRASILIERA DE PESQUISAS E DESENVOLVIMENTO LTDA. (BR) 1987-03-18 EP claimed
WO-1986005400-A1 ANTIGENS, ANTIBODIES AND THEIR USES AXON HEALTHCARE LTD. (GB) 1986-09-25 WO claimed
EP-0063352-B1 PROCESS FOR PREPARING 5-FLUOROCYTOSINE SALT Daikin Kogyo Co., Ltd. (JP) 1986-07-23 EP claimed
EP-0094329-B1 TANNING PROCESS FOR RENDERING LEATHERS MYCOSTATIC, ANTIMYCOSIC AND ANTIFUNGICIDAL, AND ARTICLES PRODUCED THEREBY Roux, Joel (FR) 1986-01-22 EP claimed
US-4521406-A COMBINATION OF 5-FLUOROCYTOSINE AND CYTOSINEDEAMINASE CHISSO CORPORATION (JP) 1985-06-04 US claimed
EP-0126684-A2 Drug delivery system utilizing thermosetting gels MERCK & CO. INC. (US) 1984-11-28 EP claimed
US-4484925-A USING BIOCIDAL AGENTS ON METAL COMPLEXES ROUX JOEL (FR) 1984-11-27 US claimed
US-4474751-A SUSTAINED RELEASE USING AN ALKYLENEDIAMINE-MODIFIED ETHYLENE OXIDE-PROPYLENE OXIDE COPOLYMER MERCK & CO., INC. (US) 1984-10-02 US claimed
US-4168206-A Impregnated disk method for testing antifungal susceptibility PHILADELPHIA COLLEGE OF OSTEOPATHIC MEDICINE (US) 1979-09-18 US claimed