Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2405529 | 0.80 | SIGMAR1 (0.44) | SIGMAR1ALDH1A1HSD17B10TSHRTP53 | |
| SCHEMBL2404555 | 0.77 | CCR5 (0.44) | SIGMAR1ALDH1A1RAB9ATSHRTP53 | |
| SCHEMBL5207755 | 0.76 | ALDH1A1 (0.59) | ALDH1A1RAB9AGAAHSD17B10HPGD | |
| SCHEMBL15563386 | 0.75 | ALDH1A1 (0.52) | ALDH1A1RAB9AGAAHSD17B10HPGD | |
| SCHEMBL1468159 | 0.75 | ALDH1A1 (0.62) | ALDH1A1RAB9AGAAHSD17B10HPGD | |
| SCHEMBL8572280 | 0.75 | CYP3A4 (0.62) | SIGMAR1ALDH1A1RAB9AHSD17B10HPGD | |
| SCHEMBL16491229 | 0.74 | SIGMAR1 (0.47) | SIGMAR1ALDH1A1RAB9AGAAHSD17B10 | |
| SCHEMBL2407533 | 0.74 | KCNH2 (0.49) | SIGMAR1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL2405156 | 0.74 | CCR5 (0.60) | SIGMAR1RAB9ANPC1CCR5 | |
| SCHEMBL286952 | 0.74 | ALDH1A1 (0.60) | ALDH1A1RAB9AGAAHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | HCRTR2, HCRTR1, HRH3 | SIGMAR1 108/4885ALDH1A1 2292/4885RAB9A 2150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.