Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.38 |
| ▸ | CDK4 | P11802 | 4/20 | 0.37 |
| ▸ | CCND1 | P24385 | 4/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | MC5R | P33032 | 1/20 | 0.34 |
| ▸ | MC3R | P41968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2408924 | 0.94 | HTR1A (0.42) | HTR1ACDK4CCND1HCRTR2HTR2A | |
| SCHEMBL2405605 | 0.94 | CDK4 (0.39) | CDK4CCND1HCRTR2HCRTR1HTR2A | |
| SCHEMBL2408939 | 0.91 | HCRTR1 (0.39) | CDK4CCND1HCRTR2HCRTR1SLC6A4 | |
| SCHEMBL2407464 | 0.91 | CDK4 (0.47) | CDK4CCND1HCRTR2BCHEACHE | |
| SCHEMBL2407863 | 0.90 | HCRTR2 (0.42) | CDK4CCND1HCRTR2HCRTR1HTR2A | |
| SCHEMBL2407843 | 0.89 | ICMT (0.41) | HTR1ACDK4CCND1HCRTR2HCRTR1 | |
| SCHEMBL2406479 | 0.87 | HTR2A (0.39) | CDK4CCND1HCRTR2HCRTR1HTR2A | |
| SCHEMBL2403499 | 0.87 | MPO (0.38) | CDK4CCND1HCRTR2HCRTR1SLC6A4 | |
| SCHEMBL2404560 | 0.87 | ICMT (0.39) | HTR1ACDK4CCND1HCRTR2HCRTR1 | |
| SCHEMBL2403908 | 0.86 | HCRTR2 (0.42) | HTR1ACDK4CCND1HCRTR2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-01 | — | — | US | claimed |
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | HCRTR2, HCRTR1, HRH3 | HTR1A 56/4885CDK4 3031/4885CCND1 3178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.