Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22680985 | 0.80 | TRPA1 (0.38) | TRPA1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL31073547 | 0.64 | — | — | |
| SCHEMBL24851003 | 0.64 | — | — | |
| SCHEMBL9190672 | 0.64 | TRPA1 (0.55) | TRPA1ALDH1A1CYP3A4HPGDALOX15 | |
| Diallyldisulfide SCHEMBL93944 | 0.63 | — | — | |
| Diallyldisulfide SCHEMBL18687005 | 0.63 | TRPA1 (1.00) | TRPA1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL24064583 | 0.62 | TRPA1 (0.40) | TRPA1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL15299758 | 0.61 | — | — | |
| SCHEMBL12773085 | 0.61 | — | — | |
| SCHEMBL1814740 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210371446-A1 | SIRT1 ACTIVATING COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2021-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210371446-A1 | SIRT1 ACTIVATING COMPOUNDS | SIRT1, SIRT2, SIRT3 | TRPA1 2496/4885ALDH1A1 616/4885CYP3A4 4172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.