SCHEMBL24065950

SCHEMBL24065950

O=C(O)CSCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.39
HIF1A Q16665 1/20 0.39
THRB P10828 2/20 0.38
GMNN O75496 1/20 0.36
TP53 P04637 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C9 P11712 1/20 0.36
BLM P54132 1/20 0.36
HSD17B10 Q99714 1/20 0.36
BHMT Q93088 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.31
CES1 P23141 2/20 0.31
MMP12 P39900 1/20 0.31
MMP13 P45452 1/20 0.31
MVD P53602 1/20 0.31
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24065889 1.00 CYP2D6 (0.39) CYP2D6HIF1ATHRBGMNNTP53
SCHEMBL9943886 0.87 THRB (0.43) CYP2D6HIF1ATHRBGMNNTP53
SCHEMBL7138008 0.87 CYP2D6 (0.32) CYP2D6HIF1ATHRB
SCHEMBL9943488 0.84 CYP2D6 (0.46) CYP2D6HIF1ATHRBGMNNTP53
SCHEMBL23350859 0.84 LMNA (0.50) THRBHSD17B10BHMTCYP2C19
SCHEMBL13883931 0.84 LMNA (0.50) THRBHSD17B10BHMTCYP2C19
SCHEMBL9943837 0.81 GMNN (0.44) CYP2D6HIF1ATHRBGMNNTP53
SCHEMBL9943893 0.80 GMNN (0.47) CYP2D6HIF1ATHRBGMNNTP53
SCHEMBL24065969 0.80 KDM1A (0.32) CES1
SCHEMBL7723019 0.80 LMNA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210369846-A1 New Ammonium Salts Of Fluorinated Organic Acids, Method Of Their Synthesis and Application NANOSANGUIS (PL) 2021-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210369846-A1 New Ammonium Salts Of Fluorinated Organic Acids, Method Of Their Synthesis and Application APOB, PHOSPHO1, ALB CYP2D6 1995/4885HIF1A 3583/4885THRB 4071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.