Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.55 |
| ▸ | CTSS | P25774 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12658511 | 0.95 | CTSK (0.50) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL21419058 | 0.91 | CTSK (0.52) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL28000286 | 0.91 | CTSK (0.52) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL17627333 | 0.88 | CTSK (0.47) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL17498476 | 0.88 | CTSK (0.47) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL22359140 | 0.87 | CTSK (0.46) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL1951088 | 0.84 | CTSS (0.67) | CTSKCTSSKMT2A | |
| SCHEMBL3205842 | 0.84 | CTSS (0.67) | CTSKCTSSKMT2A | |
| SCHEMBL629960 | 0.84 | CTSS (0.67) | CTSKCTSSKMT2A | |
| SCHEMBL3825684 | 0.84 | CTSS (0.67) | CTSKCTSSKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11358950-B2 | SMAC mimetics used as IAP inhibitors and use thereof | CHIA TAI TIANGQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2022-06-14 | — | — | US | disclosed |
| US-20210371400-A1 | SMAC MIMETICS USED AS IAP INHIBITORS AND USE THEREOF | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2021-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210371400-A1 | SMAC MIMETICS USED AS IAP INHIBITORS AND USE THEREOF | BIRC7, BIRC5, BIRC2 | CTSK 2434/4885CTSS 2441/4885MEN1 1310/4885 |
| US-11358950-B2 | SMAC mimetics used as IAP inhibitors and use thereof | BIRC7, BIRC5, BIRC2 | CTSK 2434/4885CTSS 2441/4885MEN1 1310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.