Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3110474 | 0.80 | TDP1 (0.56) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL16367913 | 0.74 | DPP4 (0.55) | TAAR1HTR2AGBA1HRH1 | |
| SCHEMBL6859196 | 0.74 | DPP4 (0.55) | TAAR1HTR2AGBA1HRH1 | |
| SCHEMBL2521653 | 0.74 | DPP4 (0.55) | TAAR1HTR2AGBA1HRH1 | |
| SCHEMBL6859189 | 0.74 | DPP4 (0.55) | TAAR1HTR2AGBA1HRH1 | |
| SCHEMBL5914545 | 0.70 | TAAR1 (0.48) | HIF1ATAAR1LMNA | |
| SCHEMBL6856102 | 0.70 | TAAR1 (0.48) | HIF1ATAAR1LMNA | |
| SCHEMBL13995085 | 0.70 | TAAR1 (0.48) | HIF1ATAAR1LMNA | |
| SCHEMBL11415966 | 0.70 | TAAR1 (0.48) | HIF1ATAAR1LMNASLC6A3 | |
| SCHEMBL3905889 | 0.70 | SIGMAR1 (0.54) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210371382-A1 | HYDROGENATION OF IMINES WITH RU COMPLEXES | FIRMENICH SA (CH) | 2021-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210371382-A1 | HYDROGENATION OF IMINES WITH RU COMPLEXES | HRH3, HRH4, HRH2 | ALDH1A1 2869/4885CYP3A4 2019/4885ALOX15 4706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.