Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | SCN4A | P35499 | 4/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16367913 | 1.00 | DPP4 (0.55) | DPP4F2SCN4AHTR2ATAAR1 | |
| SCHEMBL6859189 | 1.00 | DPP4 (0.55) | DPP4F2SCN4AHTR2ATAAR1 | |
| SCHEMBL2521653 | 1.00 | DPP4 (0.55) | DPP4F2SCN4AHTR2ATAAR1 | |
| SCHEMBL11415966 | 0.85 | TAAR1 (0.48) | SCN4ATAAR1 | |
| SCHEMBL5914545 | 0.85 | TAAR1 (0.48) | DPP4F2SCN4ATAAR1 | |
| SCHEMBL28853589 | 0.85 | SCN4A (0.47) | DPP4F2SCN4AHTR2ATAAR1 | |
| SCHEMBL3701549 | 0.85 | SCN4A (0.47) | DPP4F2SCN4AHTR2ATAAR1 | |
| SCHEMBL13995085 | 0.85 | TAAR1 (0.48) | DPP4F2SCN4ATAAR1 | |
| SCHEMBL6856102 | 0.85 | TAAR1 (0.48) | DPP4F2SCN4ATAAR1 | |
| Hydrochloric Acid SCHEMBL16292126 | 0.83 | ALDH1A1 (0.48) | DPP4F2SCN4ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039675-B2 | Catalysts | JOHNSON MATTHEY PLC (GB) | 2011-10-18 | — | — | US | disclosed |
| US-20100197976-A1 | CATALYSTS | JOHNSON MATTHEY PLC (GB) | 2010-08-05 | — | — | US | disclosed |
| EP-1849792-B1 | Biphosphine ruthenium complexes with chiral diamine ligands as catalysts | JOHNSON MATTHEY PLC (GB) | 2008-12-10 | — | — | EP | disclosed |
| US-6790973-B2 | REDUCTION OF KETONE TO ALCOHOL USING COMPLEX CATALYST | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2004-09-14 | — | — | US | disclosed |
| US-20030166978-A1 | Novel ruthenium complexes and process for preparing alcoholic compounds using these | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2003-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197976-A1 | CATALYSTS | HRH3, HRH2, PRMT8 | DPP4 4328/4885F2 1047/4885SCN4A 4104/4885 |
| US-20030166978-A1 | Novel ruthenium complexes and process for preparing alcoholic compounds using these | ADH1C, ADH1A, ADH5 | DPP4 4409/4885F2 577/4885SCN4A 3938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.