Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132688 | 0.83 | TDP1 (0.52) | TDP1CYP3A4TSHRALDH1A1ALOX15 | |
| SCHEMBL24067992 | 0.80 | ALDH1A1 (0.46) | TDP1CYP3A4TSHRALDH1A1ALOX15 | |
| SCHEMBL94935 | 0.79 | ALDH1A1 (0.77) | TDP1CYP3A4TSHRALDH1A1ALOX15 | |
| SCHEMBL13776661 | 0.79 | ALDH1A1 (0.77) | TDP1CYP3A4TSHRALDH1A1ALOX15 | |
| SCHEMBL27960166 | 0.79 | TDP1 (0.58) | TDP1CYP3A4TSHRALDH1A1ALOX15 | |
| SCHEMBL8744834 | 0.79 | TDP1 (0.58) | TDP1CYP3A4TSHRALDH1A1ALOX15 | |
| SCHEMBL172358 | 0.79 | ALDH1A1 (0.77) | TDP1CYP3A4TSHRALDH1A1ALOX15 | |
| SCHEMBL23569545 | 0.78 | ALDH1A1 (0.61) | TDP1CYP3A4TSHRALDH1A1ALOX15 | |
| SCHEMBL10889115 | 0.78 | ALDH1A1 (0.50) | TDP1CYP3A4TSHRALDH1A1ALOX15 | |
| SCHEMBL10589375 | 0.77 | TDP1 (0.56) | TDP1CYP3A4TSHRALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114507164-B | Gemini surfactant, preparation method, composition and application thereof | 中国石油天然气股份有限公司 | 2023-10-24 | — | — | CN | claimed |
| JP-8253456-A | — | — | None | — | — | JP | disclosed |
| EP-4326813-A1 | POLYISOBUTENE DERIVATIVES AS AN ADDITIVE IN RUBBERS | BASF SE (DE) | 2024-02-28 | — | — | EP | disclosed |
| US-11866547-B2 | Method for producing functionalized polyesters | HENKEL AG & CO. KGAA (DE) | 2024-01-09 | — | — | US | disclosed |
| US-20230100838-A1 | COVALENT RAS INHIBITORS AND USES THEREOF | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-03-30 | — | — | US | disclosed |
| EP-3428216-B1 | METHOD FOR PRODUCING FUNCTIONALIZED POLYESTERS | HENKEL AG & CO KGAA (DE) | 2022-11-02 | — | — | EP | disclosed |
| WO-2022223345-A1 | POLYISOBUTENE DERIVATIVES AS AN ADDITIVE IN RUBBERS | BASF SE (DE) | 2022-10-27 | — | — | WO | disclosed |
| CN-114980976-A | Covalent RAS inhibitors and uses thereof | 锐新医药公司 | 2022-08-30 | — | — | CN | disclosed |
| WO-2021108683-A1 | COVALENT RAS INHIBITORS AND USES THEREOF | Revolution Medicines, Inc. (US) | 2021-06-03 | — | — | WO | disclosed |
| US-20200140609-A1 | Method for Producing Functionalized Polyesters | HENKEL IBERICA S.A. (ES) | 2020-05-07 | — | — | US | disclosed |
| US-20100179282-A1 | POLYESTERS CONTAINING AMINO GROUPS | EVONIK DEGUSSA GMBH (DE) | 2010-07-15 | — | — | US | disclosed |
| EP-1877401-A2 | NOVEL COMPOUNDS USEFUL FOR BRADYKININ B1 RECEPTOR ANTAGONISM | Elan Pharmaceuticals Inc. (US) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006113140-A2 | NOVEL COMPOUNDS USEFUL FOR BRADYKININ B1 RECEPTOR ANTAGONISM | ELAN PHARMACEUTICALS, INC. (US) | 2006-10-26 | — | — | WO | disclosed |
| JP-H08253456-A | 2-PERHYDROPYRIMIDINONE DERIVATIVE, HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT AND INTERMEDIATE FOR PRODUCING THE SAME | MITSUBISHI CHEM CORP | 1996-10-01 | — | — | JP | disclosed |
| US-5059391-A | USE OF POLYARALKYLAMINES AS CORROSION INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-10-22 | — | — | US | disclosed |
| US-4922021-A | ANTIARRHYTHMIA AGENTS | BASF AKTIENSELLSCHAFT (DE) | 1990-05-01 | — | — | US | disclosed |
| EP-0306831-A1 | Use of polyaralkyl amines as corrosion inhibitors | BAYER AG (DE) | 1989-03-15 | — | — | EP | disclosed |
| EP-0114374-B1 | SUBSTITUTED 4-AMINOMETHYLENE CHROMANS OR CHROMENES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES | BAYER AG (DE) | 1986-07-23 | — | — | EP | disclosed |
| US-4563458-A | CIRCULATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1986-01-07 | — | — | US | disclosed |
| EP-0114374-A1 | Substituted 4-aminomethylene chromans or chromenes, process for their preparation and their use in medicines | BAYER AG (DE) | 1984-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230100838-A1 | COVALENT RAS INHIBITORS AND USES THEREOF | KRAS, NRAS, HRAS | TDP1 2909/4885CYP3A4 3657/4885TSHR 3138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.