Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30605033 | 1.00 | ALDH1A1 (0.36) | ALDH1A1KDM4EPOLBCSNK1A1CLK4 | |
| SCHEMBL4413387 | 0.83 | ALDH1A1 (0.40) | ALDH1A1KDM4EPOLBCSNK1A1CLK4 | |
| SCHEMBL1697925 | 0.81 | HTT (0.34) | HTT | |
| SCHEMBL11086636 | 0.80 | ALDH1A1 (0.44) | ALDH1A1KDM4EPOLBCSNK1A1CLK4 | |
| SCHEMBL29380304 | 0.78 | ALDH1A1 (0.38) | ALDH1A1KDM4EPOLBCSNK1A1CLK4 | |
| SCHEMBL1338461 | 0.78 | ALDH1A1 (0.38) | ALDH1A1KDM4EPOLBCSNK1A1CLK4 | |
| SCHEMBL31307776 | 0.78 | HTT (0.39) | ALDH1A1KDM4EPOLBCSNK1A1CLK4 | |
| SCHEMBL1697862 | 0.78 | HTT (0.39) | ALDH1A1KDM4EPOLBCSNK1A1CLK4 | |
| SCHEMBL882394 | 0.75 | HTT (0.41) | CSNK1A1CLK4HTT | |
| SCHEMBL28477092 | 0.75 | ALDH1A1 (0.36) | ALDH1A1KDM4EPOLBCSNK1A1CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113735785-B | Preparation method of 3, 6-dichloropyrazine-2-carbonitrile | 南京桦冠生物技术有限公司 | 2023-10-13 | — | — | CN | disclosed |
| US-20230103507-A1 | METHOD FOR PREPARING 3,6-DICHLOROPYRAZINE-2-CARBONITRILE | NANJING CHEMPION BIOTECHNOLOGY CO.,LTD. (CN) | 2023-04-06 | — | — | US | disclosed |
| WO-2021237945-A1 | METHOD FOR PREPARING 3,6-DICHLOROPYRAZINE-2-CARBONITRILE | 南京桦冠生物技术有限公司 | 2021-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230103507-A1 | METHOD FOR PREPARING 3,6-DICHLOROPYRAZINE-2-CARBONITRILE | PFAS, ITPA, EIF4A2 | ALDH1A1 1489/4885KDM4E 2857/4885POLB 692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.