SCHEMBL24070359

SCHEMBL24070359

N#Cc1c(F)cc(F)c(C#N)c1C#N

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 3/20 0.59
EGLN2 Q96KS0 2/20 0.33
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
DHODH Q02127 1/20 0.32
KHK P50053 1/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
KDM4E B2RXH2 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MEN1 O00255 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7868318 0.86 TRPV4 (0.52) TRPV4EGLN2
SCHEMBL9490015 0.85 TRPV4 (0.56) TRPV4EGLN2ESR1ESR2DHODH
SCHEMBL29728453 0.80 TRPV4 (0.52) TRPV4EGLN2
SCHEMBL16127308 0.80 TRPV4 (0.52) TRPV4DHODHALDH1A1HPGDKDM4E
SCHEMBL809217 0.80 TRPV4 (0.52) TRPV4EGLN2
SCHEMBL24253799 0.80 TRPV4 (0.52) TRPV4EGLN2KDM4E
SCHEMBL185766 0.79 TRPV4 (0.64) TRPV4EGLN2ESR1ESR2DHODH
SCHEMBL809118 0.79 TRPV4 (0.50) TRPV4ESR1ESR2DHODHKHK
Potassium Ion SCHEMBL22396365 0.78 TRPV4 (0.56) TRPV4EGLN2
SCHEMBL4323122 0.78 TRPV4 (0.48) TRPV4ESR1ESR2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230131274-A1 P-TYPE ORGANIC SEMICONDUCTOR MATERIAL, MANUFACTURING METHOD OF SAME, AND DISPLAY PANEL WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-04-27 US disclosed
WO-2021237820-A1 P-TYPE ORGANIC SEMICONDUCTOR MATERIAL, PREPARATION METHOD AND DISPLAY PANEL 武汉华星光电半导体显示技术有限公司 2021-12-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230131274-A1 P-TYPE ORGANIC SEMICONDUCTOR MATERIAL, MANUFACTURING METHOD OF SAME, AND DISPLAY PANEL SELP, ATP5PO, PTPRO TRPV4 707/4885EGLN2 1555/4885ESR1 680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.