SCHEMBL24253799

SCHEMBL24253799

N#Cc1c(F)cc(F)c(C#N)c1I

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 3/20 0.52
EGLN2 Q96KS0 2/20 0.31
TTR P02766 1/20 0.31
ALB P02768 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3842293 0.83 TRPV4 (0.46) TRPV4
SCHEMBL24070359 0.80 TRPV4 (0.59) TRPV4EGLN2KDM4E
SCHEMBL732229 0.79 TRPV4 (0.58) TRPV4EGLN2TTRALB
SCHEMBL31353077 0.78 TRPV4 (0.42) TRPV4
SCHEMBL9490015 0.78 TRPV4 (0.56) TRPV4EGLN2
SCHEMBL29914996 0.77 TRPV4 (0.39) TRPV4KDM4E
SCHEMBL27002519 0.77 TRPV4 (0.39) TRPV4KDM4E
SCHEMBL29176715 0.75 TRPV4 (0.39) TRPV4TTRALBKDM4E
SCHEMBL24108186 0.74 TRPV4 (0.38) TRPV4
SCHEMBL809217 0.74 TRPV4 (0.52) TRPV4EGLN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220052264-A1 LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220052264-A1 LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE CRY1, CRY2, ELP1 TRPV4 2190/4885EGLN2 2723/4885TTR 4356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.