SCHEMBL809217

SCHEMBL809217

N#Cc1c(F)cc(F)c(F)c1F

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 3/20 0.52
STAT3 P40763 1/20 0.31
CA1 P00915 3/20 0.31
CA2 P00918 3/20 0.31
EGLN2 Q96KS0 2/20 0.31
CA4 P22748 2/20 0.31
CA12 O43570 1/20 0.31
CA7 P43166 1/20 0.31
CA13 Q8N1Q1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29728453 1.00 TRPV4 (0.52) TRPV4STAT3CA1CA2EGLN2
SCHEMBL28699020 0.91 TRPV4 (0.45) TRPV4STAT3CA1CA2CA4
SCHEMBL9490015 0.89 TRPV4 (0.56) TRPV4EGLN2
SCHEMBL7868318 0.84 TRPV4 (0.52) TRPV4CA1CA2EGLN2CA4
SCHEMBL809118 0.83 TRPV4 (0.50) TRPV4STAT3CA1CA2CA4
SCHEMBL24070359 0.80 TRPV4 (0.59) TRPV4EGLN2
SCHEMBL7866631 0.80 TRPV4 (0.45) TRPV4STAT3
SCHEMBL8046873 0.80 TRPV4 (0.48) TRPV4
SCHEMBL27264861 0.80 TRPV4 (0.43) TRPV4EGLN2
SCHEMBL4436602 0.78 TRPV4 (0.41) TRPV4STAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
US-20250359476-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES KYULUX INC (JP) 2025-11-20 US disclosed
US-12369492-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2025-07-22 US disclosed
EP-4498784-A2 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES Kyulux, Inc. (JP) 2025-01-29 EP disclosed
EP-3775100-B1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES KYULUX INC (JP) 2025-01-22 EP disclosed
CN-114751890-B Organic compound based on binaphthyl amine derivative and organic electroluminescent device 季华恒烨(佛山)电子材料有限公司 2023-11-17 CN disclosed
CN-114751890-A Organic compound based on binaphthylamine derivative and organic electroluminescent device 季华恒烨(佛山)电子材料有限公司 2022-07-15 CN disclosed
CN-114105894-A Light-emitting compound, light-emitting layer material, organic electroluminescent device, and electronic apparatus 季华实验室 2022-03-01 CN disclosed
US-20210135119-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES KYULUX, INC. (JP) 2021-05-06 US disclosed
US-20210135119-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES KYULUX, INC. (JP) 2021-05-06 US disclosed
US-6624336-B1 Acetalization of tetrafluorobenzonitriles using alcohols, in the presence of mineral acids and metal catalysts to form chemical intermediates for nontoxic insecticides SHOWA DENKO K.K. (JP) 2003-09-23 US disclosed
US-20030158444-A1 Production process for halogenated aromatic methylamine SHOWA DENKO K.K. (JP) 2003-08-21 US disclosed
US-20030098229-A1 Photooxidation catalyst and production process for aldehyde derivatives SHOWA DENKO K.K. 2003-05-29 US disclosed
WO-2002102760-A1 PRODUCTION PROCESS FOR HALOGENATED AROMATIC METHYLAMINE SHOWA DENKO K.K. (JP) 2002-12-27 WO disclosed
CN-1349484-A Process for producing tetrafluorobenzyl alcohol SHOWA DENKO KK (JP) 2002-05-15 CN disclosed
EP-1182184-A1 PROCESS FOR PRODUCING TETRAFLUORO BENZENEMETHANOLS Showa Denko K K (JP) 2002-02-27 EP disclosed
US-6020517-A Process for production of benzonitrile and benzyl alcohol SHOWA DENKO K.K. (JP) 2000-02-01 US disclosed
EP-0270964-B1 PROCESS FOR OBTAINING SUBSTITUTED FLUOROBENZENES BAYER AG (DE) 1992-07-08 EP disclosed
US-4868347-A SOLVENT EXTRACTION BAYER AKTIENGESELLSCHAFT (DE) 1989-09-19 US disclosed
EP-0270964-A2 Process for obtaining substituted fluorobenzenes BAYER AG (DE) 1988-06-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030098229-A1 Photooxidation catalyst and production process for aldehyde derivatives AOX1, PPOX, NOX4 TRPV4 4137/4885STAT3 4008/4885CA1 1508/4885
US-20030158444-A1 Production process for halogenated aromatic methylamine NPM1, INMT, HNMT TRPV4 3369/4885STAT3 3655/4885CA1 1476/4885
US-20210135119-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES CRY2, SLCO1B3, NDUFV3 TRPV4 227/4885STAT3 4547/4885CA1 2255/4885
US-20250359476-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES CRY2, SLCO1B3, NDUFV3 TRPV4 227/4885STAT3 4547/4885CA1 2255/4885
US-12369492-B2 Composition of matter for use in organic light-emitting diodes CRY2, SLCO1B3, NDUFV3 TRPV4 227/4885STAT3 4547/4885CA1 2255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.