Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.36 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21937407 | 0.82 | NOX4 (0.42) | NQO2KDM4ECYP19A1NOX4PLA2G7 | |
| SCHEMBL23341812 | 0.82 | NQO2 (0.40) | NQO2KDM4ECYP19A1NOX4PLA2G7 | |
| SCHEMBL25696492 | 0.76 | NQO2 (0.36) | NQO2KDM4ECYP19A1PLA2G7ALDH1A1 | |
| SCHEMBL22016779 | 0.69 | KDM4E (0.40) | KDM4ENOX4ALDH1A1LMNAADORA3 | |
| SCHEMBL24759396 | 0.68 | LMNA (0.40) | KDM4ENOX4ALDH1A1LMNAADORA3 | |
| SCHEMBL21074872 | 0.67 | MEN1 (0.41) | KDM4EALDH1A1LMNAMAPTPOLB | |
| SCHEMBL21146243 | 0.66 | — | — | |
| SCHEMBL25606083 | 0.64 | LMNA (0.33) | LMNAADORA3 | |
| SCHEMBL24730692 | 0.64 | — | — | |
| SCHEMBL25879990 | 0.64 | LMNA (0.31) | LMNAADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239058-A1 | FUSED TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2021-12-02 | — | — | WO | disclosed |