⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14226080 | 0.83 | — | — | |
| SCHEMBL14226089 | 0.82 | — | — | |
| SCHEMBL21843903 | 0.78 | — | — | |
| SCHEMBL8330118 | 0.66 | — | — | |
| SCHEMBL10093812 | 0.65 | LMNA (0.31) | — | |
| SCHEMBL24070512 | 0.64 | NQO2 (0.39) | — | |
| SCHEMBL21843901 | 0.64 | — | — | |
| SCHEMBL21843900 | 0.63 | ALDH1A1 (0.33) | — | |
| SCHEMBL21843905 | 0.62 | KDM4E (0.35) | — | |
| SCHEMBL23341812 | 0.61 | NQO2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239645-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| US-20230173078-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-06-08 | — | — | US | disclosed |
| WO-2022247770-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海璎黎药业有限公司 | 2022-12-01 | — | — | WO | disclosed |