Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK7 | P50613 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | CCNH | P51946 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25239947 | 0.77 | BTK (0.33) | — | |
| SCHEMBL24439554 | 0.76 | — | — | |
| SCHEMBL23541705 | 0.70 | NLRP3 (0.34) | DRD2DRD3CCNT1CDK7CDK9 | |
| SCHEMBL25241414 | 0.70 | GABRP (0.39) | — | |
| SCHEMBL23541720 | 0.70 | NLRP3 (0.34) | DRD2DRD3CCNT1CDK7CDK9 | |
| Hydrochloric Acid SCHEMBL25234883 | 0.67 | — | — | |
| SCHEMBL25280086 | 0.66 | GAA (0.40) | — | |
| SCHEMBL25233396 | 0.64 | BTK (0.37) | — | |
| SCHEMBL20412497 | 0.61 | HRH4 (0.33) | DRD2DRD3HRH4HRH3 | |
| SCHEMBL24439814 | 0.58 | DRD2 (0.36) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239643-A1 | BENZYLAMINE DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2021-12-02 | — | — | WO | disclosed |