SCHEMBL24070709

SCHEMBL24070709

N#Cc1c(F)c(N)c(N)c(F)c1C#N

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.35
ALDH1A1 P00352 2/20 0.33
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31
PTPN1 P18031 1/20 0.31
MAPK1 P28482 2/20 0.30
MEN1 O00255 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9224728 0.91 TRPV4 (0.33) TRPV4ALDH1A1
SCHEMBL25778066 0.88 TRPV4 (0.35) TRPV4ALDH1A1ADORA2AADORA1PTPN1
SCHEMBL25778158 0.85 TRPV4 (0.33) TRPV4ALDH1A1MAPK1RECQL
SCHEMBL5154882 0.85 TRPV4 (0.33) TRPV4
SCHEMBL9849624 0.82 TRPV4 (0.37) TRPV4
SCHEMBL9225315 0.80 TRPV4 (0.31) TRPV4ALDH1A1
SCHEMBL8080367 0.79 TRPV4 (0.41) TRPV4ALDH1A1MAPK1MEN1TP53
SCHEMBL9154264 0.79 TRPV4 (0.39) TRPV4MAPK1RECQL
SCHEMBL9688285 0.79 TRPV4 (0.39) TRPV4
SCHEMBL5155293 0.77 TRPV4 (0.37) TRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230131274-A1 P-TYPE ORGANIC SEMICONDUCTOR MATERIAL, MANUFACTURING METHOD OF SAME, AND DISPLAY PANEL WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-04-27 US disclosed
WO-2021237820-A1 P-TYPE ORGANIC SEMICONDUCTOR MATERIAL, PREPARATION METHOD AND DISPLAY PANEL 武汉华星光电半导体显示技术有限公司 2021-12-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230131274-A1 P-TYPE ORGANIC SEMICONDUCTOR MATERIAL, MANUFACTURING METHOD OF SAME, AND DISPLAY PANEL SELP, ATP5PO, PTPRO TRPV4 707/4885ALDH1A1 2097/4885ADORA2A 1602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.