SCHEMBL5155293

SCHEMBL5155293

N#Cc1c(N)c(F)c(F)c(F)c1F

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8895828 0.92 TRPV4 (0.36) TRPV4
SCHEMBL9225315 0.92 TRPV4 (0.31) TRPV4
SCHEMBL9849624 0.89 TRPV4 (0.37) TRPV4
SCHEMBL9688285 0.86 TRPV4 (0.39) TRPV4
SCHEMBL9224728 0.86 TRPV4 (0.33) TRPV4
SCHEMBL5154882 0.86 TRPV4 (0.33) TRPV4
SCHEMBL169613 0.80 ALDH1A1 (0.39)
SCHEMBL9154264 0.80 TRPV4 (0.39) TRPV4
SCHEMBL30542039 0.78 TRPV4 (0.39) TRPV4
SCHEMBL809214 0.78 TRPV4 (0.39) TRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8268979-A None JP disclosed
CN-107915647-B Synthetic method of 2,3,5,6-tetrafluoroaniline 大连奇凯医药科技有限公司 2020-02-28 CN disclosed
CN-107915647-B Synthetic method of 2,3,5,6-tetrafluoroaniline 大连奇凯医药科技有限公司 2020-02-28 CN disclosed
EP-1229015-B1 Method for production of aromatic compounds NIPPON CATALYTIC CHEM IND (JP) 2007-01-10 EP disclosed
CN-1235867-C Method for preparing aromatics NIPPON CATALYTIC CHEM IND (JP) 2006-01-11 CN disclosed
US-6521794-B2 Hydrolyzing and decarboxylating an aromatic cyano compound in an acidic substance NIPPON SHOKUBAI CO., LTD. (JP) 2003-02-18 US disclosed
US-20020156322-A1 Method for production of aromatic compounds NIPPON SHOKUBAI CO., LTD. (JP) 2002-10-24 US disclosed
CN-1369479-A Method for preparing aromatics NIPPON CATALYTIC CHEM IND (JP) 2002-09-18 CN disclosed
EP-1229015-A1 Method for production of aromatic compounds Nippon Shokubai Co., Ltd. (JP) 2002-08-07 EP disclosed
JP-H08268979-A PRODUCTION OF 2,3,5,6-TETRAFLUOROANILINE NIPPON SHOKUBAI CO LTD 1996-10-15 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020156322-A1 Method for production of aromatic compounds DDC, PAH, MCCC2 TRPV4 404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.