SCHEMBL240711

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31342106	0.86	ALDH1A1 (0.50)	ALDH1A1LMNAMAPTMAPK1GFER
	SCHEMBL31342050	0.86	ALDH1A1 (0.50)	ALDH1A1LMNAMAPTMAPK1GFER
	SCHEMBL236849	0.82	DHFR (0.46)	ALDH1A1LMNAMAPTMAPK1GFER
	SCHEMBL17264125	0.81	MAPT (0.61)	ALDH1A1LMNAMAPTMAPK1GFER
	SCHEMBL6052389	0.80	KDM4E (0.50)	ALDH1A1LMNAMAPTDHFRHTT
	SCHEMBL12074106	0.80	ALDH1A1 (0.59)	ALDH1A1LMNAMAPTMAPK1GFER
	SCHEMBL11159388	0.79	MAPT (0.50)	ALDH1A1LMNAMAPTMAPK1GFER
	SCHEMBL3656158	0.79	ALDH1A1 (0.59)	ALDH1A1LMNAMAPTMAPK1GFER
	SCHEMBL17265648	0.79	ALDH1A1 (0.77)	ALDH1A1LMNAMAPTMAPK1GFER
	SCHEMBL3028930	0.78	ALDH1A1 (0.69)	ALDH1A1LMNAMAPTMAPK1GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.