Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | STAT3 | P40763 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 8/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31665510 | 0.87 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2ALDH1A1MITF | |
| SCHEMBL25142631 | 0.87 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2ALDH1A1MITF | |
| SCHEMBL24072268 | 0.87 | MAPK14 (0.47) | ADORA2ASTAT3RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24073697 | 0.86 | ADORA2A (0.45) | ADORA2ASTAT3RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24073698 | 0.86 | STAT3 (0.52) | STAT3RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24073701 | 0.84 | POLQ (0.47) | STAT3RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24072763 | 0.83 | ADORA2A (0.43) | ADORA2ASTAT3RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24072273 | 0.81 | TP53 (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1MITF | |
| SCHEMBL24072282 | 0.81 | CCNE1 (0.41) | STAT3RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24072346 | 0.81 | STAT3 (0.41) | ADORA2ASTAT3RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239117-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI) , INC. (CN) | 2021-12-02 | — | — | WO | disclosed |