Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MITF | O75030 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 2/20 | 0.39 |
| ▸ | KLK1 | P06870 | 2/20 | 0.39 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | FADS1 | O60427 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24073698 | 0.85 | STAT3 (0.52) | STAT3ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL24072268 | 0.83 | MAPK14 (0.47) | CCNE1CDK2CDK5STAT3ALDH1A1 | |
| SCHEMBL24072759 | 0.83 | CDK2 (0.40) | CCNE1CDK2CDK5STAT3ALDH1A1 | |
| SCHEMBL24073701 | 0.82 | POLQ (0.47) | STAT3ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL24072284 | 0.81 | ADORA2A (0.44) | STAT3ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL25063151 | 0.81 | STAT3 (0.64) | STAT3ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL24072271 | 0.81 | ITK (0.43) | STAT3ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL24072346 | 0.81 | STAT3 (0.41) | STAT3ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL24072273 | 0.81 | TP53 (0.48) | ALDH1A1RAB9ASMN1; SMN2NPC1MITF | |
| SCHEMBL24074132 | 0.79 | ALDH1A1 (0.54) | STAT3ALDH1A1RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239117-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI) , INC. (CN) | 2021-12-02 | — | — | WO | disclosed |