Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | STAT3 | P40763 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | EIF2S1 | P05198 | 1/20 | 0.37 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24072284 | 0.87 | ADORA2A (0.44) | ADORA2ASTAT3ALDH1A1NPC1MITF | |
| SCHEMBL25063464 | 0.84 | MAPK14 (0.43) | MAPK14ADORA2ASTAT3LCKALDH1A1 | |
| SCHEMBL24072282 | 0.83 | CCNE1 (0.41) | MAPK14STAT3ALDH1A1NPC1MITF | |
| SCHEMBL24073698 | 0.83 | STAT3 (0.52) | STAT3ALDH1A1NPC1MITFLMNA | |
| SCHEMBL25063046 | 0.82 | STAT3 (0.62) | ADORA2ASTAT3ALDH1A1NPC1LMNA | |
| SCHEMBL24073701 | 0.81 | POLQ (0.47) | STAT3ALDH1A1NPC1MITFLMNA | |
| SCHEMBL24072346 | 0.79 | STAT3 (0.41) | ADORA2ASTAT3ALDH1A1NPC1MITF | |
| SCHEMBL24072273 | 0.79 | TP53 (0.48) | ALDH1A1NPC1MITFLMNARAB9A | |
| SCHEMBL24072271 | 0.79 | ITK (0.43) | STAT3ALDH1A1NPC1MITFLMNA | |
| SCHEMBL24074132 | 0.77 | ALDH1A1 (0.54) | ADORA2ASTAT3ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239117-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI) , INC. (CN) | 2021-12-02 | — | — | WO | disclosed |