Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | F2R | P25116 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | PLK1 | P53350 | 3/20 | 0.40 |
| ▸ | LCK | P06239 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 2/20 | 0.37 |
| ▸ | AXL | P30530 | 3/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 3/20 | 0.37 |
| ▸ | MERTK | Q12866 | 3/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24073630 | 0.87 | ALDH1A1 (0.41) | F2RALDH1A1NPC1MITFLMNA | |
| SCHEMBL24073700 | 0.86 | MAPK14 (0.42) | ADORA2AF2RMAPK14PLK1LCK | |
| SCHEMBL27136866 | 0.85 | PLK1 (0.41) | ADORA2AF2RMAPK14PLK1LCK | |
| SCHEMBL24072486 | 0.85 | ALDH1A1 (0.43) | ADORA2AF2RPLK1ALDH1A1STAT3 | |
| SCHEMBL30142841 | 0.84 | STAT3 (0.58) | ADORA2AALDH1A1STAT3NPC1LMNA | |
| SCHEMBL25063073 | 0.84 | STAT3 (0.58) | ADORA2AALDH1A1STAT3NPC1LMNA | |
| SCHEMBL24072284 | 0.83 | ADORA2A (0.44) | ADORA2AALDH1A1STAT3KITNPC1 | |
| SCHEMBL25142388 | 0.82 | RAB9A (0.46) | ADORA2AALDH1A1NPC1MITFLMNA | |
| SCHEMBL25142407 | 0.81 | RAB9A (0.45) | ADORA2AALDH1A1NPC1MITFLMNA | |
| SCHEMBL27134564 | 0.81 | ALDH1A1 (0.48) | ALDH1A1NPC1MITFLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239117-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI) , INC. (CN) | 2021-12-02 | — | — | WO | disclosed |