Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PNLIP | P16233 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24073630 | 0.87 | ALDH1A1 (0.41) | ALDH1A1LMNAGAATDP1MAPK1 | |
| SCHEMBL24073700 | 0.87 | MAPK14 (0.42) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30142728 | 0.84 | ATG4B (0.54) | ALDH1A1LMNAMAPK1MEN1KMT2A | |
| SCHEMBL25063086 | 0.84 | ATG4B (0.54) | ALDH1A1LMNAMAPK1MEN1KMT2A | |
| SCHEMBL27134459 | 0.80 | ALDH1A1 (0.53) | ALDH1A1LMNAGAAMEN1KMT2A | |
| SCHEMBL24072486 | 0.78 | ALDH1A1 (0.43) | ALDH1A1LMNAGAAMAPK1MEN1 | |
| SCHEMBL24073964 | 0.78 | ALDH1A1 (0.39) | ALDH1A1LMNAGAAMAPK1ALOX15 | |
| SCHEMBL24074042 | 0.76 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPK1MEN1KMT2A | |
| SCHEMBL25063112 | 0.76 | ATG4B (0.52) | ALDH1A1LMNATDP1MAPK1MEN1 | |
| SCHEMBL30142823 | 0.76 | ATG4B (0.52) | ALDH1A1LMNATDP1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239117-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI) , INC. (CN) | 2021-12-02 | — | — | WO | disclosed |