Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24074052 | 0.93 | MEN1 (0.42) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL24072486 | 0.87 | ALDH1A1 (0.43) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL24072238 | 0.86 | LMNA (0.43) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL24072349 | 0.86 | F2R (0.39) | ALDH1A1SMN1; SMN2ADORA2AF2RPNLIP | |
| SCHEMBL27136866 | 0.85 | PLK1 (0.41) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL24073964 | 0.85 | ALDH1A1 (0.39) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL25063310 | 0.84 | STAT3 (0.64) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL24072300 | 0.82 | ALDH1A1 (0.43) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL24074000 | 0.81 | F2R (0.41) | ALDH1A1TP53F2RPLK1CDK2 | |
| SCHEMBL24072333 | 0.81 | F2R (0.42) | ALDH1A1MEN1KMT2AF2RPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239117-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI) , INC. (CN) | 2021-12-02 | — | — | WO | disclosed |