Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 0.50 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 4/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | PDE11A | Q9HCR9 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | ABL2 | P42684 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19264154 | 0.86 | SRC (0.67) | SRCADKEGFRCDK1PDE11A | |
| SCHEMBL24072905 | 0.84 | SRC (0.50) | SRCADKCA12CA1CA2 | |
| SCHEMBL22032001 | 0.82 | SRC (0.50) | SRCADKCA12CA1CA2 | |
| SCHEMBL22084743 | 0.77 | SRC (0.84) | SRCCA12CA1CA2CA9 | |
| SCHEMBL22086335 | 0.76 | SRC (0.39) | SRCADKCA12CA1CA2 | |
| SCHEMBL20351787 | 0.75 | LMNA (0.50) | SRCADKMEN1KMT2ARXFP1 | |
| SCHEMBL22086070 | 0.74 | SRC (0.84) | SRCCA12CA1CA2CA9 | |
| SCHEMBL6935719 | 0.72 | ADK (0.48) | SRCADKCA12CA1CA2 | |
| SCHEMBL2785304 | 0.72 | SRC (0.49) | SRCADKCA12CA1CA2 | |
| SCHEMBL22086034 | 0.71 | SRC (0.54) | SRCCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021242505-A1 | INHIBITORS OF NEK7 KINASE | Halia Therapeutics, Inc. (US) | 2021-12-02 | — | — | WO | disclosed |