Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.46 |
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24073357 | 0.83 | RAB9A (0.43) | RAB9ANPC1SMN1; SMN2LMNAMAPT | |
| SCHEMBL24073356 | 0.78 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL24072625 | 0.78 | HDAC6 (0.50) | RAB9ANPC1SMN1; SMN2LMNAMAPT | |
| SCHEMBL27334977 | 0.76 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2LMNAMAPT | |
| SCHEMBL28969074 | 0.74 | SLC17A5 (0.45) | RAB9ANPC1SMN1; SMN2LMNAMAPT | |
| SCHEMBL30306867 | 0.74 | SLC17A5 (0.45) | RAB9ANPC1SMN1; SMN2LMNAMAPT | |
| SCHEMBL28969076 | 0.74 | SLC17A5 (0.45) | RAB9ANPC1SMN1; SMN2LMNAMAPT | |
| SCHEMBL30306805 | 0.73 | HDAC1 (0.40) | RAB9ANPC1SMN1; SMN2LMNAMAPT | |
| SCHEMBL25023561 | 0.71 | MEN1 (0.49) | RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL3118574 | 0.69 | MAPT (0.61) | RAB9ANPC1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021242923-A1 | TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | AXIAL THERAPEUTICS, INC. (US) | 2021-12-02 | — | — | WO | disclosed |