Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20952174 | 0.77 | MAPT (0.56) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27334960 | 0.77 | CTNNB1 (0.60) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8717367 | 0.76 | KMT2A (0.55) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL25253664 | 0.76 | HDAC6 (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL29502366 | 0.76 | HDAC6 (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL24073353 | 0.76 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL2244369 | 0.76 | KMT2A (0.58) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8712740 | 0.75 | KMT2A (0.54) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL19914214 | 0.75 | RAF1 (0.57) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6002245 | 0.75 | KMT2A (0.70) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097355-A1 | DEUBIQUITINASE-TARGETING CHIMERAS AND RELATED METHODS | VICINITAS THERAPEUTICS, INC. (US) | 2024-05-10 | — | — | WO | disclosed |
| WO-2024097355-A1 | DEUBIQUITINASE-TARGETING CHIMERAS AND RELATED METHODS | VICINITAS THERAPEUTICS, INC. (US) | 2024-05-10 | — | — | WO | disclosed |