SCHEMBL2407351

SCHEMBL2407351

[c]1cccc2c1c1[c]cccc1c1ccccc21

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 1/20 0.35
CYP1A2 P05177 3/20 0.32
ALDH1A1 P00352 2/20 0.32
HSD17B10 Q99714 2/20 0.32
THRB P10828 1/20 0.32
HPGD P15428 1/20 0.32
CYP2A6 P11509 2/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4824194 0.94 HPRT1 (0.35) HPRT1CYP1A2ALDH1A1HSD17B10THRB
SCHEMBL24104 0.94 HPRT1 (0.35) HPRT1CYP1A2ALDH1A1HSD17B10THRB
SCHEMBL2413265 0.91 HPRT1 (0.36) HPRT1CYP1A2ALDH1A1HSD17B10THRB
SCHEMBL2409495 0.91 CYP2A6 (0.33) HPRT1CYP1A2ALDH1A1HSD17B10CYP2A6
SCHEMBL534967 0.85 ALDH1A1 (0.37) CYP1A2ALDH1A1HSD17B10THRBHPGD
SCHEMBL18221932 0.81 ALDH1A1 (0.39) HPRT1CYP1A2ALDH1A1HSD17B10THRB
SCHEMBL5028366 0.81 PADI4 (0.38) ALDH1A1HSD17B10THRBHPGDTSHR
SCHEMBL28496768 0.81 CYP1A2 (0.33) CYP1A2HSD17B10HPGDCYP2A6TSHR
SCHEMBL534952 0.79 HPRT1 (0.58) HPRT1CYP1A2ALDH1A1HSD17B10THRB
SCHEMBL2411457 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011105700-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2011-09-01 WO disclosed