SCHEMBL2413265

SCHEMBL2413265

[c]1cc[c]c2c1c1ccccc1c1ccccc21

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 1/20 0.36
ALDH1A1 P00352 3/20 0.33
HSD17B10 Q99714 3/20 0.33
CYP1A2 P05177 3/20 0.33
CYP2A6 P11509 2/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
THRB P10828 1/20 0.33
HPGD P15428 1/20 0.33
IDO1 P14902 1/20 0.32
GPR3 P46089 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2407351 0.91 HPRT1 (0.35) HPRT1ALDH1A1HSD17B10CYP1A2CYP2A6
SCHEMBL24104 0.85 HPRT1 (0.35) HPRT1ALDH1A1HSD17B10CYP1A2CYP2A6
SCHEMBL4824194 0.85 HPRT1 (0.35) HPRT1ALDH1A1HSD17B10CYP1A2CYP2A6
SCHEMBL2409495 0.81 CYP2A6 (0.33) HPRT1ALDH1A1HSD17B10CYP1A2CYP2A6
SCHEMBL534967 0.76 ALDH1A1 (0.37) ALDH1A1HSD17B10CYP1A2THRBHPGD
SCHEMBL510638 0.73 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10CYP1A2CYP2A6
SCHEMBL5028366 0.73 PADI4 (0.38) ALDH1A1HSD17B10TSHRTDP1THRB
SCHEMBL28496768 0.73 CYP1A2 (0.33) HSD17B10CYP1A2CYP2A6TSHRHPGD
SCHEMBL18221932 0.73 ALDH1A1 (0.39) HPRT1ALDH1A1HSD17B10CYP1A2CYP2A6
SCHEMBL534952 0.71 HPRT1 (0.58) HPRT1ALDH1A1HSD17B10CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011105700-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2011-09-01 WO disclosed