Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25063293 | 0.87 | PRSS12 (0.41) | STAT3KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL24072387 | 0.85 | KDM4E (0.44) | STAT3KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL24072280 | 0.82 | SMN1; SMN2 (0.47) | KMT2AMEN1ALDH1A1RAB9ALMNA | |
| SCHEMBL13044975 | 0.81 | ALDH1A1 (0.48) | STAT3KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL12697305 | 0.79 | MEN1 (0.50) | KMT2AMEN1LMNAMAPT | |
| SCHEMBL24072749 | 0.77 | STAT3 (0.41) | STAT3KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL24072715 | 0.77 | TRPV1 (0.45) | STAT3KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL25142470 | 0.77 | RAB9A (0.55) | KMT2ADYRK1AMEN1ALDH1A1NPC1 | |
| SCHEMBL31665172 | 0.77 | RAB9A (0.55) | KMT2ADYRK1AMEN1ALDH1A1NPC1 | |
| SCHEMBL27134415 | 0.77 | RAB9A (0.44) | STAT3KMT2AMEN1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239117-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI) , INC. (CN) | 2021-12-02 | — | — | WO | disclosed |