Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24074074 | 0.93 | RAB9A (0.43) | ALDH1A1RAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL24072438 | 0.86 | ALDH1A1 (0.43) | ALDH1A1RAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL25063314 | 0.83 | STAT3 (0.65) | ALDH1A1RAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL24074042 | 0.82 | ALDH1A1 (0.42) | ALDH1A1RAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL24072388 | 0.82 | ALDH1A1 (0.42) | ALDH1A1RAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL24074055 | 0.81 | ALDH1A1 (0.45) | ALDH1A1RAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL24072238 | 0.81 | LMNA (0.43) | ALDH1A1RAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL24074070 | 0.81 | ALDH1A1 (0.50) | ALDH1A1RAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL13044208 | 0.78 | ALDH1A1 (0.65) | ALDH1A1RAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL24074052 | 0.77 | MEN1 (0.42) | ALDH1A1RAB9ASMN1; SMN2NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239117-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI) , INC. (CN) | 2021-12-02 | — | — | WO | disclosed |