SCHEMBL2407452

SCHEMBL2407452

CCNC(N)CO[Si](CCc1ccccc1)(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.36
SMN1; SMN2 Q16637 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
TACR1 P25103 1/20 0.32
POLB P06746 1/20 0.32
LAP3 P28838 1/20 0.32
MGLL Q99685 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3484430 0.77 HTR2A (0.37) SIGMAR1SMN1; SMN2TACR1
SCHEMBL10696910 0.76 TDP1 (0.39) SMN1; SMN2NPC1RAB9A
SCHEMBL27849515 0.76 TDP1 (0.33) SIGMAR1NPC1RAB9A
SCHEMBL2488885 0.75 HTR2A (0.42) SMN1; SMN2
SCHEMBL106416 0.74 TDP1 (0.46) SMN1; SMN2NPC1RAB9A
SCHEMBL6332013 0.73 RAB9A (0.38) SIGMAR1SMN1; SMN2NPC1RAB9A
SCHEMBL28118715 0.72 SLC6A2 (0.40) SIGMAR1
SCHEMBL11252138 0.72 HTR2A (0.44) SMN1; SMN2
SCHEMBL1765960 0.71 TDP1 (0.47) SMN1; SMN2NPC1RAB9APOLB
SCHEMBL1968087 0.71 TDP1 (0.38) SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1106977-A Metallic foil with adhesion promoting layer COULD ELECTRONICS INC (US) 1995-08-16 CN claimed
CN-104892975-B The method for preparing the rubber composition of filling 株式会社普利司通 2017-07-25 CN disclosed
EP-2539394-B1 RUBBER COMPOSITIONS INCLUDING SILICEOUS FILLERS BRIDGESTONE CORP (JP) 2014-11-19 EP disclosed
EP-2539394-A2 RUBBER COMPOSITIONS INCLUDING SILICEOUS FILLERS Bridgestone Corporation (JP) 2013-01-02 EP disclosed
WO-2011106765-A2 RUBBER COMPOSITIONS INCLUDING SILICEOUS FILLERS BRIDGESTONE CORPORATION (JP) 2011-09-01 WO disclosed
EP-2014692-A2 Polyisocyanates containing allophanate and silane groups Bayer MaterialScience AG (DE) 2009-01-14 EP disclosed
CN-1106977-A Metallic foil with adhesion promoting layer COULD ELECTRONICS INC (US) 1995-08-16 CN disclosed