Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 7/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.39 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24075354 | 0.83 | L3MBTL1 (0.44) | L3MBTL1GAATDP1ERN1KDM4E | |
| SCHEMBL30067006 | 0.81 | ERN1 (0.59) | L3MBTL1GAAERN1KDM4EKMT2A | |
| SCHEMBL3008338 | 0.81 | ERN1 (0.59) | L3MBTL1GAAERN1KDM4EKMT2A | |
| SCHEMBL28821423 | 0.79 | ERN1 (0.41) | L3MBTL1GAATDP1ERN1KDM4E | |
| SCHEMBL28821420 | 0.79 | ERN1 (0.41) | L3MBTL1GAATDP1ERN1KDM4E | |
| SCHEMBL25834578 | 0.78 | LMNA (0.42) | L3MBTL1KDM4EKMT2APOLBSMN1; SMN2 | |
| SCHEMBL24075355 | 0.78 | POLB (0.46) | L3MBTL1KDM4EKMT2APOLBSMN1; SMN2 | |
| SCHEMBL5755021 | 0.77 | ERN1 (0.52) | L3MBTL1GAAERN1KDM4EKMT2A | |
| SCHEMBL5755022 | 0.75 | ERN1 (0.54) | L3MBTL1GAAERN1KDM4EKMT2A | |
| SCHEMBL5755025 | 0.75 | ERN1 (0.52) | L3MBTL1GAAERN1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239077-A1 | MLL1 INHIBITORS AND ANTI-CANCER AGENTS | NOVARTIS AG (CH) | 2021-12-02 | — | — | WO | disclosed |