Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.73 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.73 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.73 |
| ▸ | XPO1 | O14980 | 2/20 | 0.73 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.73 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.73 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.73 |
| ▸ | MAOA | P21397 | 1/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.64 |
| ▸ | CASP1 | P29466 | 3/20 | 0.64 |
| ▸ | CASP7 | P55210 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 5/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16352043 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1CYP3A4PTGS2ABCB1 | |
| Osthole SCHEMBL50436 | 0.84 | PTGS2 (1.00) | KDM4EALDH1A1CYP3A4PTGS2ABCB1 | |
| Osthole SCHEMBL29595542 | 0.84 | PTGS2 (1.00) | KDM4EALDH1A1CYP3A4PTGS2ABCB1 | |
| Osthole SCHEMBL17513161 | 0.84 | PTGS2 (1.00) | KDM4EALDH1A1CYP3A4PTGS2ABCB1 | |
| Osthole SCHEMBL27681201 | 0.83 | PTGS2 (0.97) | KDM4EALDH1A1CYP3A4PTGS2ABCB1 | |
| Osthole SCHEMBL27950752 | 0.83 | PTGS2 (0.97) | KDM4EALDH1A1CYP3A4PTGS2ABCB1 | |
| SCHEMBL14316132 | 0.83 | CA9 (0.71) | KDM4EALDH1A1CYP3A4PTGS2ABCB1 | |
| Osthole SCHEMBL27803504 | 0.81 | PTGS2 (0.92) | KDM4EALDH1A1CYP3A4PTGS2ABCB1 | |
| SCHEMBL30379956 | 0.80 | PDE4D (0.81) | KDM4EALDH1A1CYP3A4PTGS2ABCB1 | |
| Osthole SCHEMBL27659943 | 0.80 | PTGS2 (0.90) | KDM4EALDH1A1CYP3A4PTGS2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795127-B2 | Processes for the preparation of ortho-allylated hydroxy aryl compounds | MCMASTER UNIVERSITY (CA) | 2023-10-24 | — | — | US | disclosed |
| US-11795127-B2 | Processes for the preparation of ortho-allylated hydroxy aryl compounds | MCMASTER UNIVERSITY (CA) | 2023-10-24 | — | — | US | disclosed |
| US-20230113567-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | MCMASTER UNIVERSITY (CA) | 2023-04-13 | — | — | US | disclosed |
| US-20210380513-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | MCMASTER UNIVERSITY (CA) | 2021-12-09 | — | — | US | disclosed |
| WO-2021237371-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | MCMASTER UNIVERSITY (CA) | 2021-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230113567-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | ADH1A, ADH1C, AHR | KDM4E 2010/4885ALDH1A1 52/4885CYP3A4 151/4885 |
| US-20210380513-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | ADH1A, ADH1C, AHR | KDM4E 2010/4885ALDH1A1 52/4885CYP3A4 151/4885 |
| US-11795127-B2 | Processes for the preparation of ortho-allylated hydroxy aryl compounds | ADH1A, ADH1C, AHR | KDM4E 2010/4885ALDH1A1 52/4885CYP3A4 151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.