Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29727327 | 1.00 | P2RX3 (0.36) | P2RX3SLC29A1FGFR1FGFR4PDE4A | |
| SCHEMBL28821449 | 1.00 | P2RX3 (0.36) | P2RX3SLC29A1FGFR1FGFR4PDE4A | |
| SCHEMBL31028254 | 0.92 | P2RX3 (0.39) | P2RX3SLC29A1FGFR1FGFR4PDE4A | |
| SCHEMBL24075634 | 0.90 | DOT1L (0.37) | SLC29A1FGFR1FGFR4PDE4APDE4B | |
| SCHEMBL28948817 | 0.90 | SLC29A1 (0.35) | P2RX3SLC29A1FGFR1FGFR4PDE4A | |
| SCHEMBL28948818 | 0.90 | SLC29A1 (0.35) | P2RX3SLC29A1FGFR1FGFR4PDE4A | |
| SCHEMBL28821343 | 0.89 | NSD2 (0.36) | P2RX3SLC29A1FGFR1FGFR4AAK1 | |
| SCHEMBL28821345 | 0.89 | NSD2 (0.36) | P2RX3SLC29A1FGFR1FGFR4AAK1 | |
| SCHEMBL24075628 | 0.85 | SLC29A1 (0.35) | P2RX3SLC29A1FGFR1FGFR4PDE4A | |
| SCHEMBL24075629 | 0.84 | EP300 (0.36) | P2RX3SLC29A1FGFR1FGFR4PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929705-A | MLL1 inhibitor and anticancer agent | 诺华公司 | 2022-08-19 | — | — | CN | disclosed |
| WO-2021239077-A1 | MLL1 INHIBITORS AND ANTI-CANCER AGENTS | NOVARTIS AG (CH) | 2021-12-02 | — | — | WO | disclosed |